BK virus may have prostate cancer played a very important role

Now there are many viruses found with cancer-related, such as hepatitis B with the hepatitis C virus with liver cancer-related, EB virus with lymphoma or nasopharyngeal carcinoma, and human papillomavirus with cervical cancer or head and neck cancer. The University of Rome Italy Pietropaolo doctors found the incidence of prostate cancer may be related with the BK virus, he detected 26 patients with blood, urine, fresh prostate cancer tissue samples, but also detected a large tumor BK virus antigen (TAg) and the tumor suppressor gene p53 in tumor cells, BK virus DNA sequence in the urine samples in 54 percent accounted for, in the blood accounted for 31% of prostate cancer specimens in fresh high up to 85%, it is interesting that these prostate cancer with p53 mutations, p53 is a cancer suppressor gene. BK virus, they found a large tumor antigen in the presence of cancer cells, p53 exists in the cytoplasm of tumor cells, if TAg-negative tumors, p53 in the cell nucleus, the speculation TAg cytoplasm in cancer cells so that p53 is not activated, leading to cancer disease, and this is a very interesting finding, but the BK virus in prostate cancer incidence is playing a major role or a supporting role, it also requires long-term research in order to make conclusions.