Recurrence rate of breast cancer and hormone preparations subcutaneous (goserelin) can be reduced

Breast cancer has become the first women in the top ten cancer, an average of 19 people with breast cancer. Traditional pre-menopausal breast cancer patients will be given after tamoxifen anti-hormone therapy to reduce breast cancer recurrence rate. The latest study found that if the patients without the use of tamoxifen, such as the phenomenon of hot flashes that the poor efficacy of the proposed formulations with subcutaneous hormone (goserelin), in order to increase the rate of breast cancer control, to avoid tumor recurrence. 

 National Cheng Kung University breast surgeon Dr. Tsai-Wang pointed out that in the treatment of breast cancer, the anti-hormone therapy of estrogen receptor-positive is very important in patients with postoperative adjuvant therapy. For pre-menopausal breast cancer patients, the medical community over the years has been the use of tamoxifen as a major anti-hormone therapy drugs, the delay for patients with early breast cancer recurrence and metastasis of breast cancer the opportunity; for advanced disease and metastasis of breast cancer suffering can be achieved to reduce the deterioration of the tumor and alleviate the effects of breast cancer for many years with proven experience in the use of a percent lower mortality rate. 

 Dr. Tsai-Wang pointed out that although the efficacy of tamoxifen has its own, but many patients with a long time because of their hot flashes caused much distress and other side effects, some people even want to stop there. However, according to at American Society of Clinical Oncology December and well-known in the Lancet journal published research has shown that taking tamoxifen have hot flashes phenomenon that drugs be effective, and this has become the treatment of breast cancer important drug reference. 

 Choi Chang-wang said that the medical community understand the indicators, the use of tamoxifen for the poor efficacy of the proposed merger of subcutaneous hormone preparations at the same time (goserelin) use, facilities play a month, allowing dormant ovaries, patients with lower hormone concentration, help control the tumor cells. According to clinical trials confirmed that agents with subcutaneous hormone (goserelin) can reduce the recurrence rate of one percent. The most important thing is, once about two years after the end of treatment, ovarian function can return to normal. 

 Choi Chang-wang said that the breast cancer three years and seven years after the peak period of recurrence of breast cancer, it is proposed to be immediately after the use of anti-hormone therapy to strengthen the control, to avoid the recurrence of breast cancer; At the same time, studies have found that the use of tamoxifen are hot flashes response of the human body is more related enzyme activation, the current medical community has been a key gene can be detected CYD2D6, if the enzyme does not belong to the early activation of those agents with subcutaneous hormone (goserelin), in order to grasp the timing of optimal treatment. 

 In addition, there is thrombosis due to tamoxifen, endometrial thickening, fatty liver, such as side effects, so for endometrial cancer, the risk of thrombosis and abnormal liver function can also use the subcutaneous hormonal agents (goserelin) in lieu of tamoxifen treatment.

The two major breast cancer misconceptions

For the two major misconceptions of breast cancer -- 

 (1) that the young will not get breast cancer; 

 (2) small chest that would not have breast cancer. 

 In addition, according to statistics and research, there are habits countries and regions, the incidence of breast cancer and the recurrence rate is less than or of the countries and regions much higher than that. 

habits it is countries such as Taiwan, Malaysia, Singapore, Hong Kong and other countries the incidence and recurrence of breast cancer (including breast and some of the lesions) than in Europe and the United States much higher, because instant noodles body itself contains a lot of the elements lead to the occurrence of breast cancer. 

 Do not instant noodles body surface and in the production process, in fact, instant noodles have the body surface of the oil contains a lot of material and chemical substances. 

 I have a friend at the instant the company to go to work, his colleagues in the production department had done an experiment on him to let him know of them in fact, instant noodles contain a lot of oily substances, the weight of a full mug so much! (Of course, depending on the brand, the amount of oily material will be different, but the number of poor will not.) And many of these oily substances and chemicals, it is a result of breast lesions and the occurrence of the biggest causes of breast cancer! 

 So, starting today, it is best to quit and some contain preservatives and other chemicals in food.

Young high-grade breast cancer early detection the survival benefit

The "leaves" of a famous singer, "Asan", died yesterday morning due to breast cancer, a 34-year-old year, it is too hush sob, to remind physicians, the study found that young breast cancer some higher grade, easy to relapse, calling young women, do not overlook health check self-censorship and the importance of early diagnosis and treatment of early detection, breast cancer survival rate is quite high. (Xu Yun Xiang reports) 

 According to statistics, the East race, including Taiwan, Singapore, Hong Kong and other countries, the peak age of onset of breast cancer compared with European and American young age, often can be seen clinically young women with breast cancer cases, in addition, some surveys also found that young women think they do not may be young, breast cancer, or more conservative, they neglect to check, resulting in the detection, the breast cancer may have been relatively late. 

 Professor of Surgery at National Taiwan University Hospital, Breast Cancer Prevention Foundation, King-Jen Chang said that the women in addition to self-examination, the importance of regular medical checks, especially in some research found that most of the younger breast cancer patients, if it is negative for hormone receptors, epidermal growth factor is not the performance or over-performance, higher grade, more rapid course of evolution or the metastasis and recurrence, if uncovered as soon as possible, and help enhance the survival rate, "Comparison of a young man, you can check through the breast ultrasound examination, age Great point, after 50 years of age, mammography acceptable, can be found relatively early stage of breast cancer cells can not touch. " 

 King-Jen Chang stressed that if the early treatment of breast cancer, in many cancers is a very good prognosis of cancer, such as clinical, some are teens, more than 20-year-old female breast cancer, because early detection, coupled with treatment, After breast cancer, but also get married and have children, family case successfully called Women Do not overlook the importance of screening by, especially those with a family history of the women, but also to be more vigilant.

Lu liver dawn! New therapies enemy from the inside out

Trojan remember is the history of ancient Greece a famous battle, and now the treatment of liver cancer, there have been similar to the Trojan horse of new technologies. Taipei Veterans General Hospital introduced radiotherapy in vivo, will have millions of radioactive yttrium 90 microspheres directly to the liver itself, from the inside out to release a high radiation dose to kill cancer cells. 

 Taipei Veterans General Hospital last year, the introduction of the "Y-90 microspheres - selective body radiotherapy," admitted a total of 41 liver cancer and other terminal cancer patients with metastasis to the liver, a good therapeutic effect. "This from the inside out of the end of radiotherapy in patients with liver cancer has provided the last chance of survival!" Taipei Veterans General Hospital Department of Radiology, said Dr. Rheun-Chuan Lee, in accordance with the present treatment, in patients with terminal liver cancer is no cure, and the radioactive element yttrium 90 microspheres provide a new hope. 

 However, this new medication therapy alone have to spend more than 40 million, pre-and postoperative examination of the patient have at their own expense, all medical expenses more than 600,000 yuan. 

 Rheun-Chuan Lee pointed out that the radioactive element Yttrium-90 containing microspheres, the diameter is very small, only about one-third of the hair, by the way angiography in the liver, from the groin into the hepatic artery within the liver directly to the microspheres blood vessels inside tumors, and then gradually released within two weeks of high-dose radiation, to kill liver tumors. 

 Rheun-Chuan Lee explained that in addition to Y-90 microspheres, the radiation from all the other outside, the radiation from the in vitro into the human body, therefore, can not be too high dose, not to harm normal tissue, and the microspheres is from the inside out , in addition to high accuracy, the radiation dose is also higher, at around the other two to three times the radiation. 

 Trojan horse as the same way the use of angiography, Y-90 microspheres was sent after the hepatic artery, it will take the initiative to look for cancer cells. Tumor blood vessels as a result of the flow near the larger, 90-yttrium microspheres target, you enter the tumor, emit radiation to kill tumor lines. 

 Rheun-Chuan Lee pointed out that the current accepted treatment of patients with Y-90 are mostly due to the failure of multi-line chemotherapy or other treatment of patients with terminal liver cancer invalid, clinical showed that after two months follow-up found that 41 patients, about tumor shrinkage or five well-controlled. 

 As to whether the Y-90 microspheres in the treatment of other cancers do? The answer is no. Linked to other organs because the blood vessels, so can not use this type of radiation "