Krestin play the role of adjuvant therapy for colorectal cancer

Colorectal cancer is a common form of cancer in Taiwan each year, many people will suffer from colorectal cancer. So far, the standard treatment of colorectal cancer remains surgical resection, as well as some cases the need to meet the post-operative adjuvant chemotherapy, including traditional 5-Fu/Leucovorin, as well as modern Xeloa, oxaliplatin, such as drugs. As for metastatic patients, then changed to chemical treatment with the drug target. 

 However, in the post-operative adjuvant chemotherapy of which, together with the immunomodulatory drugs, can cause appears to strengthen the effectiveness of the effect, for the prevention of recurrence, as well as the transfer of the remote a certain degree of contribution. Tong General Hospital blood oncology physicians are referred to Chen Yi, and in Japan, the most commonly used immunomodulatory drugs is PSK body Krestin. 

 Krestin is a versicolor mycelium from which the Polysaccharides out, at present, Taiwan is classified in Western medicine, and the Department of Health also approved for use in the treatment of digestive system cancer. Many of Japan's past studies have shown Krestin in complete resection of colorectal cancer after immunochemistry does have the role of adjuvant therapy, but most of the research because the number of subjects is too small, this study design or rigorous enough, so the medical profession there is a certain amount of controversy. 

 In 2006, the famous cancer immunotherapy among medical journals, some scholars through a rigorous comprehensive analysis, will be 1980 to 2004 on Krestin for colorectal cancer after the surgery, whether the immune adjuvant therapy for the role of chemical Research to do a comprehensive analysis. The study found the results, if the intestinal use of rectal cancer after the surgery, adjuvant chemotherapy with the Krestin, will only use than simply supporting the chemical treatment, patients can bring more benefits. For five years in terms of overall survival time were 79 percent and 72.2 percent, the difference between the two have reached statistical significance, but also found that joined the Krestin, can make a patient's risk of the risk of decline in about three-cheng. If the absence of disease on the survival time, five years are as follows: 72.2 percent, respectively, as well as 65.9 percent. 

 Doctors said Chen Yi, and based on research, Krestin is a very good immunomodulatory drugs, will be induced by interferon, IL-immune cells, such as hormones, increase the activity of natural killer cells. If the post-operative chemotherapy, which, coupled with Krestin so, than the individual but to accept chemotherapy, to patients in terms of survival time of the absence of disease or overall survival time, are able to provide substantial help to them.