Phytoestrogen is fever over the past few years is the topic, of which the most notable of soybean isoflavone. Major components of soy isoflavone are genistein, daidzein, these compounds have antioxidant properties, they are able to prevent cancer. Soy isoflavone genistein on the principal components can inhibit cell proliferation and cell differentiation, and inhibit the effect of the increase with dose. . Because genistein is an effective inhibitor of tyrosine kinase. genistein can inhibit DNA topoisomerase (DNA topoisomerases) Ⅰ and Ⅱ and its signal transduction important enzymes, so-like isoflavones in cancer prevention plays an important role.
Such phytoestrogen its structure and function in terms of both estrogen and human is very similar. In theory, this type of plant estrogen and estrogen also by competing with the in vivo estrogen receptor binding manner, making phytoestrogen had diminished as a result of female hormones to stimulate the body, thereby reducing the risk of breast cancer .
In fact really true? British research team carried out against this assumption, and a large-scale prospective study, and the results of the study published in February 2007 the well-known magazine - "Journal of Clinical Oncology."
They monitored 383 women have been suffering from breast cancer (including pre-and post-menopause) the blood concentration of plant estrogen, and the corresponding 383 women compared to normal. It was found that genistein at high concentrations in blood, their breast cancer risk will be reduced. And phytoestrogens in lignans (Lignan) the level of its value, not in any way.
Great credibility from this study, we is not hard to see, plant estrogen for breast cancer prevention is of great potential.
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