Sunday, February 15, 2009
For liver metastasis of colorectal cancer patients can not use chemoembolization may extend survival
Colorectal cancer liver are most likely to transfer the place, once the transfer, by chemical treatment such as FOLFOX part of the formula may have the patient can be reduced and surgery and chemotherapy failed surgery should not have some of the patients can use such as radiofrequency tumor ablation methods, can also be used Y90 chemoembolization or embolization, such as radiology. Recently, University Hospital Frankfurt, Germany Wolfgang physician's report, he would colorectal cancer unresectable liver metastasis failed to respond to chemotherapy and 463 patients, average age is 62.5 years old, 67.4% of patients have liver metastasis 5 points, 8% only a transfer point, 14.3% are 3-4 shift points, 10.4 percent have two transfer points. Every four weeks with chemoembolization method, with an average 5.3 times for each person, the use of drugs, including lipiodol, starch microspheres for vascular occlusion at the same time together with mitomycin C, gemcitabine or irinotecan. 463 patients 14.7% of patients have some of remission, 48.2% of patients with stable, 37.1% of patients deteriorated, one-year survival are 62% two years survival was 28%, from the beginning has an average survival of liver metastasis period is 38 months for the embolization was 14 months. With mitomycin C, gemcitabine, or irinotecan survival are the same. No statistical difference, so think Wolfgang chemoembolization for liver metastasis of colorectal cancer patients is not a very good treatment.
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