Miss Chen, this year 53-year-old, a nasopharyngeal carcinoma patients to receive the first chemotherapy combined with cisplatin Cisplatin synchronous radiotherapy, appear mild oral ulcers, and the feeling of nausea and vomiting, weight decreased from 52 kilograms to 51 kilograms. Then the second chemical treatment, oral ulcers and increase the pain associated with swelling, thereby affecting appetite, nausea and vomiting and feeling no improvement in body weight decreased from 51 kilograms to 49 kilograms, it is weak; discomfort of these symptoms, Chan made the start of treatment exclusion, confidence has been defeated. Ms Chan was recommended to receive bran acid amide adjuvant therapy, symptoms gradually improve. However, in the third after chemotherapy, oral ulcers no longer occur, the gradual return of weight, it is important that the treatment of Miss Chen regain the confidence to smoothly complete course of treatment. Another case is a 68-year-old this year, Mr. Xie, a bladder cancer patients receiving chemotherapy treatment, after one week of oral ulcers serious weight even dropped by 2 kg, the same in the supplementary bran after acid amide patients to improve the lot of oral ulcer cases, body weight also gradually resuming.
Nobody knows the past bran acid amide, until 1930, scientists have discovered in our body there is a amino acid called glutamic acid amide, are non-essential amino acids, but because gluten is the intestinal acid amide, as well as T-lymphocytes and macrophages macrophage cells essential nutrients, so it was also regarded as the intestinal tract of the amino acids necessary. Acid amide and bran can be protein diet. And in the plasma and skeletal muscle is rich in content. It is the blood levels of most amino acids, and the physiological role to play as follows:
1. Glutamic acid amide is rapidly dividing cells in the body such as the gastrointestinal mucosa, intestinal cells and immune cells: lymphocytes, macrophages of an important energy source. So with the regulation of immune and metabolic function of mucosal cells.
2. To help the liver function in newborn sugar, RNA, DAN and protein synthesis.
3. Kidney leading role in production of ammonia.
4. Help regulate the body acid-base balance.
5. For the body of nitrogen providers, the maintenance of nitrogen balance.
6. Is the in vivo antioxidant glutathione synthesis of the material before the trend, with antioxidant capacity.
7. Synthesis of Health as the body to carry out an important matter before the trend, such as nucleic acids, nucleotides and so on.
The small intestine is the consumption of bran acid amide major organs, healthy food consumption per day from 5-10 grams of glutamic acid amide, usually do not need to add another. However, if the physical pressure in the physiological conditions, intestinal acid amide bran will increase demand for the maintenance of normal intestinal metabolic function, structure and patterns. Therefore the protection and recovery of intestinal function, intestinal cell proliferation, intestinal mucus, intestinal electrolyte absorption of the amino acids necessary.
If the body is under pressure such as: surgery, sepsis, multiple trauma, cancer (particularly radiotherapy and chemical treatment) and burn cases, can cause the blood concentration of glutamic acid amide decline, the situation will so that cells within the bran acid amide reduced more than 50%. At the same time, small intestine and the immune activation of cells to bran acid amide requirements will be far higher than the amount synthesized in vivo, thus intrinsic bran acid synthesis in these circumstances can not fully make up for cells (especially skeletal muscle) glutamic acid amide the loss of volume, it shows a lack of, but also it may result in immune function recession, oral mucosa ulcer bleeding, intestinal atrophy, diarrhea and other symptoms.
Glutamic acid amide exogenous supply by peripheral intravenous infusion or by the gut to give way. Add post-operative measures to fight acid amide bran nutritional needle can improve intestinal immune function, reducing the intestinal mucosa atrophy, maintaining cells bran acid concentration, and promote the nitrogen balance, but also can prevent the transfer of bacteria to improve the intestinal feeding tolerance. In addition trauma or burn patients given enteral formula acid amide bran can reduce the pneumonia, bacteremia and septicemia from happening. It should be noted that bran acid amide metabolism in the liver and kidney, so clinical acid amide added bran also need to consider whether the patients have liver and kidney disease, in order to avoid toxicity generated.
Is now well aware that while the blood of cancer patients in the low value of bran acid amide, the added bran acid amide is useful. Cancer patients receiving chemotherapy, radiation therapy to kill the cancerous cells, but this method will also harm the host normal differentiated cells. Caused by oral inflammation, pain, nausea, vomiting, diarrhea, peripheral neuropathy and other side effects, both patients would have discomfort, resulting in reduced intake of nutrients, research confirmed that the supplementary bran acid amide can be slowed down due to chemotherapy showed that brought oral mucosa damage to the patients or pain, diarrhea and symptoms such as numbness in hands and feet feel. Animal studies also found that severe radiation-induced intestinal injury, could be supplemented by oral bran acid amide to mitigate damage. It can be seen in the chemotherapy or radiotherapy, the bran acid amide and to preserve the integrity of intestinal mucosa structure is very important. And cancer patients if the disease continues to worsen, leading to depletion of skeletal muscle amino acids, they can cause cancer cachexia situation at this time to add bran acid amide is useful. Generally speaking, for a cancer cachexia patients bran acid amide oral recommendation of 50 grams per day; and applies protective effect of radiotherapy or chemotherapy, and it is recommended three times a day, each 10 grams or a daily oral 0.5 grams per kilogram of body weight.
As to when the supplementary bran acid amide? When the emergency and the use of bran acid amide were inhibited when added bran acid amide will have optimal results. So it should be added in the organization after mucosal damage, especially in the chemotherapy before the earlier one starts to add, the better the body.
All in all, bran acid amide cancer patients not only to increase its anti-tumor immunity, increase their mucosal tissue repair capacity, thereby reducing the side effects of cancer treatment; consumption of tumor cells can also be the defense capabilities, making it more vulnerable to cancer anti-cancer drugs to kill patients. This two-way effect, quite uphold the taste. Therefore, the war against cancer, do not forget bran acid amide!
No comments:
Post a Comment