And a major breakthrough in cancer treatment! Rong-Yang team successfully separated a cause of oral cancer, head and neck cancer, brain tumors, lung cancer cell proliferation and recurrence of the root causes of the "cancer stem cells", now also have found cancer stem cells can inhibit the specific gene or protein, the future can provide new drugs development and drug screening platform, to provide tailored medical plans.
According to this new medical theory, Rong-Yang team after several years of efforts to study, since the success of oral cancer, head and neck cancer, brain tumors, and lung carcinoma patients isolated "cancer stem cells." After animal tests, a small number of cancer stem cells can form tumors in animals, the ability to generate far more than other non-"cancer stem cells" of the cancer cells, with a high degree of radiation resistance.
Experimental process, the research team will be 1000 of cancer stem cells injected into the mice, it was soon to become the tumor, usually a general tumor cells, at least 100,000 more than can be carcinogenic, and now and then inhibit a specific protein drug fight into mice, tumor that is clearly beginning to fade.
Taipei Veterans General Hospital stem cell room physician QIU Shi-hua pointed out that the traditional cancer treatment is surgical resection after radiation and chemical treatment to curb the growth of cancer cells, thereby triggering apoptosis. But a high degree of malignancy, after chemotherapy or radiotherapy, the still survive, leading to future recurrence of cancer cells, while the study found that "cancer stem cells" is caused by cancer patients the key to tumor recurrence.
This research was published in May this year, internationally renowned medical research journal PLoS ONE (Public Library), and in July will be published in Clinical Cancer Research (Clinical Cancer Research) and PLoS ONE (Public Library).
QIU Shi-hua said that the use of "cancer stem cells" will show a large number of anti-protein and high-volume decline of embryonic stem cell characteristics of regulatory proteins can inhibit them from chemotherapy and radiotherapy resistance to new drug R & D, this new research results, will be able to significantly enhance the treatment of cancer patients and the more situations.
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